SB 4.31.18
tenaikam atmanam asesa-dehinam
kalam pradhanam purusam paresam
sva-tejasa dhvasta-guna-pravaham
atmaika-bhavena bhajadhvam addha
Translation by His Divine Grace A. C. Bhaktivedanta Swami Srila Prabhupada:
Because the Supreme Lord is the cause of all causes, He is the Supersoul of all individual living entities, and He exists as both the remote and immediate cause. Since He is aloof from the material emanations, He is free from their interactions and is Lord of material nature. You should therefore engage in His devotional service, thinking yourself qualitatively one with Him.
Purport by His Divine Grace A. C. Bhaktivedanta Swami Srila Prabhupada:
According to Vedic calculations, there are three causes of creation: time, the ingredient and the creator. Combined, these are called tritayatmaka, the three causes. Everything in this material world is created by these three causes. All of these causes are found in the Personality of Godhead. As confirmed in Brahma-samhita, sarva-karana-karanam. Narada Muni therefore advises the Pracetas to worship the direct cause, the Supreme Personality of Godhead. As stated before, when the root of a tree is watered, all the parts are energized. According to the advice of Narada Muni, one should directly engage in devotional service. This will include all pious activity. Caitanya-caritamrta states, krsne bhakti kaile sarva-karma krta haya: when one worships the Supreme Lord, Krsna, in devotional service, one automatically performs all other pious activity. In this verse the words sva-tejasa dhvasta-guna-pravaham are very significant. The Supreme Personality of Godhead is never affected by the material qualities, although they all emanate from His spiritual energy. Those who are really conversant with this knowledge can utilize everything for the service of the Lord because nothing in this material world is unconnected with the Supreme Personality of Godhead.