Srimad Bhagavatam Canto 08, Chapter 07, Text 42

SB 8.7.42

tatah karatali-krtya
 vyapi halahalam visam
abhaksayan maha-devah
 krpaya bhuta-bhavanah
 
Translation by His Divine Grace A. C. Bhaktivedanta Swami Srila Prabhupada: 
 
Thereafter, Lord Siva, who is dedicated to auspicious, benevolent work for humanity, compassionately took the whole quantity of poison in his palm and drank it.
 
Purport by His Divine Grace A. C. Bhaktivedanta Swami Srila Prabhupada: 
 
Although there was such a great quantity of poison that it spread all over the universe, Lord Siva had such great power that he reduced the poison to a small quantity so that he could hold it in his palm. One should not try to imitate Lord Siva. Lord Siva can do whatever he likes, but those who try to imitate Lord Siva by smoking ganja and other poisonous things will certainly be killed because of such activities.
Srimad Bhagavatam Canto 08, Chapter 07, Text 41
Srimad Bhagavatam Canto 08, Chapter 07, Text 43