Srimad Bhagavatam Canto 10, Chapter 85, Text 15

SB 10.85.15

guna-pravaha etasminn
 abudhas tv akhilatmanah
gatim suksmam abodhena
 samsarantiha karmabhih
 
Translation: 
 
They are truly ignorant who, while imprisoned within the ceaseless flow of this world’s material qualities, fail to know You, the Supreme Soul of all that be, as their ultimate, sublime destination. Because of their ignorance, the entanglement of material work forces such souls to wander in the cycle of birth and death.
 
Purport: 
 
A soul who forgets his true identity as a servant of God is sent to this world to be imprisoned in a succession of material bodies. Wrongly identifying himself with these bodies, such a conditioned soul suffers the consequent distress of karmic action and reaction. Vasudeva, as a compassionate Vaisnava, laments for the suffering conditioned souls, whose unhappiness, the result of ignorance, can be remedied by knowledge of the principles of devotional service to Lord Krsna.
Srimad Bhagavatam Canto 10, Chapter 85, Text 14
Srimad Bhagavatam Canto 10, Chapter 85, Text 16