SB 11.25.35
sattvam cabhijayed yukto
nairapeksyena santa-dhih
sampadyate gunair mukto
jivo jivam vihaya mam
Translation:
Then, being fixed in devotional service, the sage should also conquer the material mode of goodness by indifference toward the modes. Thus pacified within his mind, the spirit soul, freed from the modes of nature, gives up the very cause of his conditioned life and attains Me.
Purport:
The word nairapeksyena refers to complete detachment from the modes of material nature. By attachment to the loving service of the Lord, which is completely transcendental, one gives up one’s interest in the modes of nature.